Topical propranolol for infantile hemangioma: a comprehensive review of mechanisms, clinical efficacy, and novel formulations
North Sichuan Medical University · University of Electronic Science and Technology of China · +4 more institutions
Abstract
Infantile hemangioma (IH) is the most common benign soft tissue tumor in children. While most exhibit a tendency for spontaneous regression, a minority can lead to severe, life-threatening complications, necessitating active intervention. Treatment modalities vary depending on the lesion's location, size, and depth. In recent years, topical β-blockers have increasingly become a preferred treatment option for many parents and clinicians. This review aims to systematically summarize the pharmacological mechanisms, clinical efficacy, safety profile, and formulation innovations of topical propranolol in the treatment of IH by synthesizing domestic and international literature, thereby providing a valuable…
Citation impact
- FWCI
- 142.75
- Percentile
- 100%
- References
- 48
Authors
11- FCFeifan Chen
North Sichuan Medical University, University of Electronic Science and Technology of China
- LYLu Yang
University of Electronic Science and Technology of China
- KLKunpeng Li
University of Electronic Science and Technology of China, Southwest Medical University
- JCJiajun Chen
Sichuan University, West China Second University Hospital of Sichuan University
- WAWenying Angela Liu
Sichuan University, West China Second University Hospital of Sichuan University
Topics & keywords
- Infantile hemangioma
- Propranolol
- Clinical Practice
- Modalities
- Clinical trial
- Clinical pharmacology