articleBrain Research BulletinJan 1, 2026GOLD OA

Disease-specific network pattern of perinatal depression revealed by Common Orthogonal Basis Extraction

University of Electronic Science and Technology of China

PubMed
Indexed incrossrefdoajpubmed

Abstract

The clinical diagnosis of perinatal depression (PD) presents considerable challenge, as it is much harder to identify than non-perinatal depression. Psychologically, common emotional fluctuations during pregnancy are easily confounded with depressive symptoms, leading to missed and incorrect diagnoses. Neurologically, pregnancy-induced alterations in brain activity could obscure neuroimaging features specific to PD. Therefore, this study introduced an innovative approach that combined brain network analysis with Common Orthogonal Basis Extraction (COBE) to identify a PD-Specific Network Pattern from resting-state brain networks, as well as validating its efficacy in diagnosis and assessment. Resting-state…

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6
total citations
FWCI
97.13
Percentile
100%
References
30
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Authors

14

Topics & keywords

Keywords
  • Neuroimaging
  • Electroencephalography
  • Support vector machine
  • Artificial neural network
  • Pattern recognition (psychology)
  • Identification (biology)
  • Depression (economics)
UN Sustainable Development Goals
  • Good health and well-being
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