Microfluidic shape-based separation for cells and particles: recent progress and future perspective
Chonnam National University · Technische Universität Ilmenau
Abstract
Shape-based separation of micro- and nanoparticles has emerged as a powerful yet underdeveloped strategy in microfluidics, offering distinct advantages over conventional size-based methods, particularly for biomedical and functional material applications. Unlike size-based separation, shape-based approaches enable discrimination between particles of identical volume but differing morphology, an essential capability for isolating pathological cells, engineered particles, or anisotropic biological entities whose function is inherently linked to shape. This review provides a comprehensive and critical overview of recent progress in both passive and active microfluidic platforms tailored for shape-selective…
Citation impact
- FWCI
- 41.32
- Percentile
- 100%
- References
- 188
Authors
7Topics & keywords
- Microfluidics
- Exploit
- Sorting
- Separation (statistics)
- Function (biology)
- Particle (ecology)