Distinct microbial mediators link diet to inflammation in Crohn’s disease and ulcerative colitis

Inflammatory bowel disease (IBD) arises from complex interactions among diet, host and gut microbiome. Although diet influences intestinal inflammation, the microbial and metabolic pathways involved, and their differences between Crohn's disease (CD) and ulcerative colitis (UC), the two main subtypes of IBD remain unclear.

To investigate how the gut microbiome mediates the effects of habitual diet on inflammatory activity in IBD.