The molecular basis of the binding and specific activation of rhizobial NodD by flavonoids
Center for Excellence in Molecular Plant Sciences · University of Chinese Academy of Sciences · +2 more institutions
Abstract
The specific partnership between legumes and rhizobia relies on a chemical dialogue. Plant flavonoids activate the bacterial transcription factor NodD, which triggers production of Nod factors that are recognized by the plant. Structural studies of the Pisum sativum (pea) symbiont Rhizobium leguminosarum NodD revealed two pockets that are essential for its activation by flavonoids. Comparative studies with NodD1 of Sinorhizobium medicae , the symbiont of Medicago truncatula , revealed that this specificity is determined by the shape of the pocket and by specific amino acids. A chimeric NodD containing the flavonoid recognition residues from S. medicae NodD1 in the R. leguminosarum NodD backbone was sufficient…
Citation impact
- FWCI
- 79.43
- Percentile
- 100%
- References
- 47
Authors
12- YRYiting RuanCorresponding
Center for Excellence in Molecular Plant Sciences, University of Chinese Academy of Sciences
- DSDong ShangZhiCorresponding
Center for Excellence in Molecular Plant Sciences
- SJSuyu Jiang
Center for Excellence in Molecular Plant Sciences
- YWYisheng Wang
Center for Excellence in Molecular Plant Sciences
- XWXiaotan Wu
Center for Excellence in Molecular Plant Sciences, University of Chinese Academy of Sciences
Topics & keywords
- Rhizobia
- Flavonoid
- Nitrogen fixation
- Bacteria
- Transcription factor
- Nod factor
- Transcription (linguistics)