Statin Therapy Independently Reduces Mortality and Liver Complications in Patients With Cirrhosis: An Updated Systematic Review and Meta‐Analysis
BDBernardo de Faria MoraesGAGustavo André Pedral Diniz LeiteIBIgor Boechat SilveiraGAGabriel André Pedral Diniz LeiteMLMaria Luisa Motta Fonseca
Universidade Federal de Minas Gerais · Universidade Federal de Juiz de Fora · +5 more institutions
Indexed incrossrefpubmed
Abstract
Background
The role of statins in cirrhosis remains controversial. Historically restricted due to safety concerns, emerging evidence highlights potential pleiotropic benefits, though effects on mortality and decompensation remain uncertain.
Aims
To evaluate the effects of statin therapy on all-cause mortality, hepatic decompensation, hepatic venous pressure gradient (HVPG), and hepatocellular carcinoma (HCC) in cirrhosis.
Citation impact
5
total citations
- FWCI
- 59.75
- Percentile
- 100%
- References
- 45
Too recent for citation history.
Authors
9- BDBernardo de Faria Moraes
Universidade Federal de Minas Gerais
- GAGustavo André Pedral Diniz Leite
Universidade Federal de Minas Gerais
- IBIgor Boechat Silveira
Universidade Federal de Juiz de Fora
- GAGabriel André Pedral Diniz Leite
Universidade Federal de Minas Gerais
- MLMaria Luisa Motta Fonseca
Pontifícia Universidade Católica do Rio Grande do Sul
Topics & keywords
Topics
Keywords
- Observational study
- Statin
- Decompensation
- MEDLINE
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Randomized controlled trial
UN Sustainable Development Goals
- Good health and well-being
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