articleNature CommunicationsJan 10, 2026GOLD OA

Closed-loop wearable neurostimulation system with triboelectric sensing to alleviate hemifacial spasms

Beijing Tsinghua Chang Gung Hospital · Tsinghua University · +3 more institutions

PubMed
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Abstract

Hemifacial spasm (HFS) is a neurological disorder characterized by involuntary contractions of the facial muscles, which can significantly influence patients’ quality of life. Traditional diagnostic methods are often subjective, and electromyography (EMG) monitoring is constrained by equipment limitations and interference. Current treatments include short-term Botulinum toxin (BTX) injections and high-risk microvascular decompression (MVD), both of which suffer from low patient compliance. This study introduces a closed-loop facial nerve stimulation system integrated into eyewear, featuring triboelectric sensors doped with butylated melamine formaldehyde (BMF)–CaCu3Ti4O12 (CCTO), and constructed with…

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