articleNeural NetworksJan 11, 2026HYBRID OA

On scientific foundation models: Rigorous definitions, key applications, and a comprehensive survey

Worcester Polytechnic Institute · Shell (India) · +1 more institution

PubMed
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Abstract

Scientific Foundation Models (SciFMs) represent a transformative paradigm for addressing complex scientific and engineering problems by leveraging large-scale pretraining and deep learning architectures. Unlike traditional numerical solvers, which require problem-specific discretization and extensive parameter tuning, SciFMs aim to learn generalizable representations of physical laws, thereby enabling broad applicability with minimal retraining. In the absence of a rigorous definition, this work categorizes their capabilities into four key dimensions-domain adaptation, domain generalization, problem adaptation, and problem generalization; thereby providing rigorous definitions for SciFMs, which we refer to as…

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5
total citations
FWCI
35.55
Percentile
100%
References
87
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Authors

7

Topics & keywords

Keywords
  • Operationalization
  • Key (lock)
  • Robustness (evolution)
  • Transformative learning
  • Domain (mathematical analysis)
  • Scientific discovery
  • Robotics
  • Deep learning
UN Sustainable Development Goals
  • Climate action
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