Robust radiomics: a review of guidelines for radiomics in medical imaging

Radiomics aims to develop image-based biomarkers by combining quantitative analysis of medical images with artificial intelligence (AI) through a robust, reproducible pipeline. Scientific societies, task groups, and consortia have published several guidelines to help researchers design robust radiomics studies. This review summarizes existing guidelines, recommendations, and regulations for designing radiomics studies that can lead to clinically adoptable biomarkers.

Relevant articles were identified through a PubMed systematic review using "radiomics" and "guideline" as keywords. Of 314 retrieved papers, after screening 99 articles were deemed relevant for extracting recommendations on developing image-based biomarkers. Additional guidelines were searched by the authors.