Therapeutic applications of cell membrane-coated nanoparticles in oral diseases: Opportunities, challenges, and future perspectives
National University of Singapore · Sun Yat-sen University · +1 more institution
Abstract
Nanotechnology holds great promise for disease therapy; however, the therapeutic efficacy of nanoparticles (NPs) is often limited by rapid recognition and clearance by the immune system. Recent studies have demonstrated that coating NPs with natural cell membranes imparts physicochemical properties closely resembling those of the source cells. This biomimetic coating also transfers key biological components, such as surface proteins and antigens, onto the NPs, endowing them with unique functionalities, including immune evasion, targeted delivery, and modulation of the immune microenvironment. These attributes underscore the significant potential of cell membrane-coated nanoparticles (CNPs) for a wide range of…
Citation impact
- FWCI
- 56.23
- Percentile
- 100%
- References
- 203
Authors
3Topics & keywords
- Immune system
- Nanomedicine
- Head and neck
- Disease
- Drug delivery
- Cell