Cyclopropane-to-organoboron conversion via C–H and C–C bond activation

Organoborons have emerged as a class of privileged building blocks in modern organic synthesis, enabling unparalleled molecular diversity and serving as versatile carboxylic acid bioisosteres with profound implications in drug discovery. Concurrently, cyclopropanes have garnered sustained attention as unique synthetic platforms, with their rigid and highly strained three-membered ring structures conferring distinctive steric and electronic properties that facilitate selective C-H and C-C activation processes. The strategic transformation of cyclopropanes into organoborons represents a particularly appealing synthetic approach, offering access to valuable molecular architectures. This review systematically…

• NN
  National Natural Science Foundation of China

  Awards: 22025104, 2022YFA1503200, 2024101703, 21972064, 22171134
• NK
  National Key Research and Development Program of China

  Award: 2022YFA1503200
• FR
  Fundamental Research Funds for the Central Universities

  Awards: 020514380352, 020514380326