Two-dimensional FeCu-metal-organic-framework boosts peroxidase activity for antibacterial application
King University · Beijing University of Chemical Technology · +2 more institutions
Abstract
The overuse of antibiotics has led to the emergence of drug-resistant bacteria, posing a serious threat to human health and increasing the medical burden. Metal–organic frameworks (MOFs) have shown great potential as enzyme mimics for antibacterial applications; however, their performance is often limited by the low density and poor accessibility of active sites. Herein, we report an innovative surface-active agent intercalation–assisted confinement growth strategy for constructing two-dimensional (2D) NH₂-BDC-Cu, Fe nanosheets (NSs) with highly exposed active site to enhance reactive oxygen species (ROS) generation, thereby improving the antibacterial efficiency against drug-resistant bacteria. We demonstrate…
Citation impact
- FWCI
- 41.46
- Percentile
- 100%
- References
- 37
Authors
12Topics & keywords
- Antibacterial activity
- Escherichia coli
- Staphylococcus aureus
- Human health
- Antibiotics
- Reactive oxygen species
- In vivo
- No poverty