Acute pancreatitis: mechanisms and therapeutic approaches

Acute pancreatitis is a complex inflammatory condition characterized by sudden onset and rapid progression, with severe cases often associated with high mortality. In recent years, the global incidence of acute pancreatitis has been increasing, with marked regional differences. This increasing trend not only places a considerable burden on healthcare systems but also significantly affects the physical and psychological well-being of patients. The most common causes-gallstone disease, hypertriglyceridemia, and alcohol abuse-also vary by region. This review provides a structured summary of current knowledge regarding the definition and classification of acute pancreatitis, along with recent advances in clinical…