articleNature HealthJan 15, 2026HYBRID OA

Large language models in global health

Singapore General Hospital · Duke-NUS Medical School · +35 more institutions

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Abstract

Large language models (LLMs) are emerging as powerful tools in healthcare, with a growing role in global health, particularly in low- and middle-income countries (LMICs). This Perspective examines the current progress, challenges and prospects of LLMs in addressing health system disparities and supporting the achievement of the Sustainable Development Goals (SDGs). While high-income countries dominate the development and deployment of LLMs, LMICs face substantial barriers. These include limited digital infrastructure, a scarcity of locally relevant data, regulatory gaps, under-representation of local languages and dialects, and challenges related to privacy and data security. The limited availability of local…

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28

Topics & keywords

Keywords
  • Global health
  • Equity (law)
  • Corporate governance
  • Sustainable development
  • Grand Challenges
  • Health equity
  • Scarcity
  • Software deployment
UN Sustainable Development Goals
  • Partnerships for the goals
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