articleScienceJan 15, 2026Closed access

Chronic low-dose exposure to chlorpyrifos reduces life span in a wild fish by accelerating aging

China University of Geosciences · Huazhong Agricultural University · +6 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Low concentrations of chemicals are widespread in the environment, but exploration of the effects of their chronic exposures on animal life span in the wild is limited. Field investigations showed that fish populations of lake skygazer ( Culter dabryi ) with chronic low-dose chlorpyrifos loads had shortened telomeres and truncated age structures. Laboratory experiments confirmed that chronic low-dose chlorpyrifos exposure induced telomere degradation and reduced survival in a dose- and physiological age–dependent manner, whereas acute high-dose exposure did not. Together, these studies provide evidence that chronic low-level chlorpyrifos exposure reduces life span and population viability in a wild fish by…

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4
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33.70
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99%
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Authors

11

Topics & keywords

Keywords
  • Chlorpyrifos
  • Life span
  • Pesticide
  • Fish <Actinopterygii>
  • Telomere
  • Population
  • Amphibian
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