articleFrontiers in Plant ScienceJan 15, 2026GOLD OA

Calcium-dependent protein kinases in plant immunity: from calcium signaling to network integration

Shanghai Institute of Technology · Dalian University of Technology

PubMed
Indexed incrossrefdoajpubmed

Abstract

In response to environmental stimuli, plants rapidly activate calcium signaling to initiate downstream responses. The transmission of calcium signals involves three primary processes: perception, decoding, and relay. Calcium-dependent protein kinases (CDPKs/CPKs), as key Ca 2+ sensors, not only detect calcium signals but also respond to them by translating these signals into physiological activities within the cell. The influx of calcium ions (Ca 2+ ) induced by pathogens triggers the conformational activation of cytosolic CPKs, which in turn enables the regulation of reactive oxygen species (ROS) production, MAPK cascades, transcriptional reprogramming, and hormone signaling. Acting as pivotal hubs in signal…

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