articleNature CommunicationsJan 16, 2026GOLD OA

Cascading chirality from molecule to twisted microstructures with amplified circularly polarized luminescence

Chinese Academy of Sciences · Beijing National Laboratory for Molecular Sciences · +2 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Control of chiral assembly across length scales is desirable but challenging. Herein, we demonstrate controllable construction of microscopic chiral twists through hierarchical assembly of enantiomeric styrylpyridinium-derived glutamide amphiphiles (L/D-SPG). By combining variable-temperature spectroscopy with in-situ real-time optical microscopic observation, the dynamic chirality transfer process across spatial and length scales during assembly is elucidated. It is revealed that hydrophobic interactions between alkyl chains and intermolecular hydrogen bonds dominate the initial assembly of SPG oligomers, which subsequently elongate into microscopic twists through synergistic action of multiple non-covalent…

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