articleEurosurveillanceJan 15, 2026DIAMOND OA

Interim vaccine effectiveness against influenza virus among outpatients, France, October 2025 to January 2026

Université de Lille · Hospices Civils de Lyon · +18 more institutions

PubMed
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Abstract

In Europe, the 2025/26 seasonal influenza epidemic started in October 2025. Co-circulation of A(H3N2) and A(H1N1)pdm09 was observed in several countries including France. We estimated early vaccine effectiveness (VE) against influenza virus in French outpatients (5,451 positives/18,816 negatives). A significant VE across all age groups was measured: 28% (95% CI: 17-37) for those aged ≥ 65 years, 45% (95% CI: 36-53) for 18-64-year-olds and 57% (95% CIs: 29-74) for 0-17-year-olds. Reinforcing vaccination uptake is warranted.

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