Association of cumulative cholesterol-HDL-glucose index with blood pressure changes and risk of new-onset hypertension in middle-aged and older adults: a cohort study

Hypertension is a major risk factor for cardiovascular diseases and represents a primary global public health concern. A newer index, the Cholesterol, High-Density Lipoprotein, and Glucose (CHG) index, has been proposed as a novel indicator for diagnosing type 2 diabetes and has recently been demonstrated to predict cardiovascular diseases (CVD). However, the associations of elevated CHG index and its cumulative measures with blood pressure changes and the new-onset hypertension risk in middle-aged and older adults remain unclear. Participants from the China Health and Retirement Longitudinal Study (CHARLS) were recruited as the longitudinal cohort for this study, with 2011 as the baseline year and follow-up…