Respiratory Support in Cardiogenic Pulmonary Edema: Clinical Insights from Cardiology and Intensive Care

Università Campus Bio-Medico · Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · +3 more institutions

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Abstract

Cardiogenic pulmonary edema (CPE) is a life-threatening manifestation of acute heart failure characterized by rapid accumulation of fluid in the interstitial and alveolar spaces, leading to severe dyspnea, hypoxemia, and respiratory failure. The condition arises from elevated left-sided filling pressures that increase pulmonary capillary hydrostatic pressure, disrupt alveolo-capillary barrier integrity, and impair gas exchange. Neurohormonal activation further perpetuates congestion and increases myocardial workload, creating a vicious cycle of hemodynamic overload and respiratory compromise. Respiratory support is a cornerstone of management in CPE, aimed at stabilizing oxygenation, reducing the work of…

Citation impact

5
total citations
FWCI
41.32
Percentile
100%
References
74
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Authors

9

Topics & keywords

Keywords
  • Extracorporeal membrane oxygenation
  • Continuous positive airway pressure
  • Mechanical ventilation
  • Intensive care
  • Hypoxemia
  • Heart failure
  • Respiratory failure
  • Cardiogenic shock
UN Sustainable Development Goals
  • Good health and well-being
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