Total cholesterol, high-density lipoprotein, and glucose (CHG) index and diabetic retinopathy in middle-aged and elderly Chinese adults with diabetes: a cross-sectional study

Evidence regarding the association between the total cholesterol, high-density lipoprotein, and glucose (CHG) index and diabetic retinopathy (DR) remains limited. This study aimed to explore the relationship between CHG and the prevalence of DR and evaluate its discriminative ability for DR.

This cross-sectional study analyzed data from 1,909 individuals with diabetes mellitus (DM), aged 45-90 years, whose information was collected between August and December 2011. To determine the association between CHG and DR, binary logistic regression models were employed. The discriminative ability of CHG for DR was assessed using receiver operating characteristic (ROC) analysis. Additionally, a series of sensitivity analyses and subgroup analyses were conducted.