articleBMC Cardiovascular DisordersJan 22, 2026GOLD OA

Trends and disparities in aortic dissection mortality in the united states: a retrospective analysis

MFMohamed Fawzi HemidaAAAlyaa Ahmed IbrahimNZNafila ZeeshanMRMohammad Rayyan FaisalKPKrish Patel

Alexandria University · Al Baha University · +12 more institutions

PubMed
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Abstract

Aortic Dissection (AD) is a life-threatening condition and one of the major causes of death in the U.S. Despite its clinical significance, trends in AD related mortality remain understudied. We aim to analyze nationwide mortality trends in AD in the U.S. Data from CDC WONDER (1999–2024) identified U.S mortality rates in adults aged ≥ 25 years with AD (ICD-10: I71.0). Crude mortality rates (CMRs) and age-adjusted mortality rates (AAMRs) per 100,000 were calculated. Trends were analyzed using Joinpoint regression to estimate annual percent change (APC) and average annual percent change (AAPC). From 1999 to 2024, a total of 115,449 deaths from AD were recorded. The AAMR increased from 2.1 in 1999 to 2.4 in 2024…

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Topics & keywords

Topics
Keywords
  • Aortic dissection
  • Mortality rate
  • Angiology
  • Retrospective cohort study
  • Population
  • Secular variation
  • Epidemiology
  • Cardiac surgery
UN Sustainable Development Goals
  • Good health and well-being
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