Self-assembling nanocomposites for smart drug delivery: towards personalized and stimuli-responsive therapeutics
University of Tehran · North Khorasan University of Medical Sciences · +4 more institutions
Abstract
Self-assembling nanocomposites (SANCs) represent a valuable and innovative drug delivery system that facilitates site-specific and stimulus-controlled drug administration. These composites have the capability to self-assemble into stimulus-responsive nanostructures, enabling the effective delivery of a wide range of therapeutic agents, from small molecules to biologics, to specific target sites. This advancement addresses crucial challenges in treating diseases like cancer and chronic inflammatory conditions. In this review, we briefly outline the advantages of SANCs in enhancing bioavailability, reducing systemic toxicity, and maintaining stability under physiological conditions. However, several significant…
Citation impact
- FWCI
- 39.96
- Percentile
- 100%
- References
- 244
Authors
12Topics & keywords
- Drug delivery
- Drug
- Targeted drug delivery
- Microsphere
- Personalized medicine
- Cancer treatment
Funding
- NRNational Research Foundation
- MOMinistry of EnvironmentAward: 2022002980004
- NRNational Research Foundation of KoreaAward: RS-2024-00406723
- MOMinistry of Education, India
- MOMinistry of Science and ICT, South KoreaAwards: RS-2025-25404986, RS-2024-00406723
- KEKorea Environmental Industry and Technology InstituteAward: 2022002980004