Spectral Fingerprinting of Engineered Nanomaterials for Precision Biosensing

Biological systems comprise a complex milieu of macromolecules, small molecules, and ions comprising tens of thousands of distinct species. Various clinical conditions alter the identities and concentrations of these species in a spatiotemporal-dependent manner. While bioanalytical methods such as omics or biochemical assays can precisely identify the targeted biomolecules over space and time, providing in-depth information on biological processes, they are generally considered low-throughput and costly. Spectral fingerprinting of engineered nanomaterials (SFEN) has emerged as an alternative method that addresses many of these limitations in the field of disease detection and chemical biology research. This…

• NS
  National Science Foundation

  Awards: 1844536, 2231621
• NI
  National Institutes of Health

  Award: R00-EB033580