articleBioengineeringJan 28, 2026GOLD OA

Integrated In Vitro, In Vivo, and In Silico Evaluation of Antioxidant, Anti-Inflammatory, Analgesic, and Anti-Arthritic Activities of Selected Marine Species

MJMd. Jahin KhandakarANAinun NaharWAWahidul AlamMJMd. Jahirul Islam MamunASAbu Sayeed Muhammad Sharif

University of Chittagong · Eastern University · +3 more institutions

PubMed
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Abstract

Marine ecosystems represent a largely untapped reservoir of bioactive compounds with significant pharmacological potential. This study aimed to evaluate the therapeutic properties of ethanol extracts from four marine species: Padina australis, Spatoglossum asperum, Holothuria (Halodeima) atra, and Hypnea valentiae. Phytochemical screening, along with a comprehensive series of in vitro, in vivo, and in silico assays, was performed to evaluate the extracts’ pharmacological activities, including antioxidant potential (2,2-diphenyl-1-picrylhydrazyl assay), anti-inflammatory effect (carrageenan-induced paw edema method), analgesic activity (acetic acid-induced writhing and tail immersion tests), and anti-arthritic…

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4
total citations
FWCI
100.11
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99%
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13

Topics & keywords

Topics
Keywords
  • Analgesic
  • Phytochemical
  • Antioxidant
  • Potency
  • Ethanol
  • In silico
UN Sustainable Development Goals
  • Life below water
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