Extraction, purification, structural elucidation, and immunomodulatory activity of Bletilla striata polysaccharides via the NF-κB signaling pathway

Introduction Bletilla striata is a traditional medicinal plant, and its polysaccharide components have been confirmed to possess immunomodulatory potential. However, most current studies focus on high-molecular-weight polysaccharides, while the immunomodulatory mechanism of low-molecular-weight polysaccharides from this plant remains unclear. This study aimed to isolate and identify a low-molecular-weight polysaccharide (BSP-2) from B. striata tubers, and to explore its immunomodulatory activity as well as the related action mechanism. Methods A neutral polysaccharide (BSP-2) was isolated from B. striata tubers. Its molecular weights were characterized using high-performance gel permeation chromatography…

• GU
  Guizhou University