A novel exopolysaccharide from Lactiplantibacillus plantarum H6 improves cholesterol metabolism via Muribaculum- mediated activation of the enterohepatic FXR–FGF15 axis
Jilin Agricultural University · East China University of Science and Technology · +1 more institution
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Abstract
H6 enhances cholesterol metabolism through microbiota-mediated activation of the enterohepatic FXR‒FGF15 axis, providing a novel therapeutic strategy for managing hypercholesterolemia.
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6Topics & keywords
Topics
Keywords
- Bile acid
- Enterohepatic circulation
- Cholesterol
- Cholesterol 7 alpha-hydroxylase
- Triglyceride
- Gut flora
- Downregulation and upregulation
- Metabolism
UN Sustainable Development Goals
- Good health and well-being
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