articleRSC AdvancesJan 1, 2026GOLD OA

The application of ICG-based photodynamic therapy combined with nanotechnology in tumor treatment

Northern Jiangsu People's Hospital · Xuzhou Medical College · +2 more institutions

PubMed
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Abstract

, poor aqueous stability, rapid systemic clearance), collectively restricting their clinical translation. Nanotechnology has become an indispensable tool to address these synergistic challenges, enabling enhanced tumor targeting, prolonged circulation time, and improved ROS generation efficiency of ICG-based PDT. This review summarizes the latest advancements in ICG-based PDT combined with nanotechnology for cancer treatment and discusses its potential and challenges in synergizing with chemotherapy and immunotherapy to amplify antitumor efficacy.

Citation impact

4
total citations
FWCI
31.97
Percentile
99%
References
98
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Authors

3

Topics & keywords

Keywords
  • Photodynamic therapy
  • Photosensitizer
  • Indocyanine green
  • Tumor microenvironment
  • Cancer treatment
  • Immunotherapy
  • Cancer therapy
  • Cancer
UN Sustainable Development Goals
  • Good health and well-being
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