articleJournal of the American Chemical SocietyFeb 5, 2026Closed access

Supramolecular-Based Ion Separation Membranes for Direct Separation of Concentrated Mixed-Salt Solutions

Hainan University · Kementerian Pendidikan Malaysia

PubMed
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Abstract

Efficient ion separation from concentrated brines is critical for sustainable water resource utilization, zero-liquid discharge, and strategic ion recovery, yet it remains a formidable challenge for conventional ion-selective membranes (ISMs). Existing ISMs rely on weak ion–pore interactions, limiting their applicability to dilute solutions, whereas stronger binding designs often impose high diffusion barriers that suppress flux. Here, we report a supramolecular ISM in which 18-crown-6 (18C6) macrocycles are integrated into the one-dimensional nanochannels of covalent organic frameworks (COFs), forming a dual-channel architecture─supramolecular pathways for cations and macrocycle-separated free channels for…

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