articleACS CatalysisFeb 7, 2026HYBRID OA

Single-Atom Catalysts at the Crossroads: Navigating the Path from Laboratory Synthesis to Real-World Devices

State Key Laboratory of Pollution Control and Resource Reuse · Nanchang Hangkong University · +3 more institutions

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Abstract

Single-atom catalysts (SACs) demonstrate immense potential in energy conversion and environmental remediation due to their extreme atomic utilization and well-defined active sites. However, transitioning SACs from laboratory research to industrial applications remains challenging because scalable and controllable synthesis must be achieved while ensuring stability and seamless integration into functional devices. This review systematically summarizes recent advances in large-scale synthesis strategies for SACs, with a focus on the scientific principles governing precursor design, coordination environment modulation, and support interactions in determining the final atomic dispersion, metal loading, and…

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