pH- and Solvent-Stable Zn II /Cd II Metal–Organic Frameworks with 2,1,3-Benzothiadiazole Derivative for Turn-On Fluorescence Sensing Dipicolinic Acid and Thiamine in Living Cells

The rapid detection of specific biological substances and biomarkers has the potential to contribute to the early identification, diagnosis, and prevention of diseases. Two examples of structurally similar luminescent metal–organic frameworks based on the same mixed ligands, namely {[M(BTBD)2(bptc)0.5]·H2O}n (M = Zn (JXUST-48) and Cd (JXUST-49), BTBD = 4,7-bis(1H-1,2,4-triazol-1-yl)-2,1,3-benzothiadiazole, H4bptc = 3,3′,5,5′-biphenyltetracarboxylic acid), have been successfully constructed using solvothermal methods. Both remain stable when immersed in organic solvents and aqueous solutions with varying pH values of 1–14 for 24 h. Interestingly, JXUST-48 can detect 2,6-pyridine dicarboxylic acid (DPA) and…

• NN
  National Natural Science Foundation of China

  Awards: 22261021, 22161019, 22061019
• NS
  Natural Science Foundation of Jiangxi Province

  Award: 20232ACB203018