Electrochemical Biosensors for Cancer Diagnosis and Prognosis Using Protein Biomarkers: Current Trends, Advances, and Clinical Translation Potential

Cancer, a disease with high mortality, represents a major public health challenge. Increased access to early tumor screening, especially non-invasive liquid biopsy assays targeting blood-circulating protein biomarkers, has advanced cancer diagnosis and treatment, but these assays are still scarce. This work critically reviews general strategies for the rapid and accurate electrochemical detection of serum proteins and surveys recent advances in liquid biopsy electrochemical biosensors targeting cancer-related proteins. Many of these approaches have achieved remarkable analytical sensitivity. The review further addresses key barriers to clinical translation and commercialization, including complex sample matrix…

• NN
  Novo Nordisk

  Award: NNF20OC0065428
• NN
  Novo Nordisk Fonden

  Award: NNF20OC0065428