Performance of the 2024 McDonald Criteria in Patients Under Evaluation for Suspected Multiple Sclerosis
Multiple Sclerosis Society · UCL Biomedical Research Centre · +5 more institutions
Abstract
We retrospectively identified patients referred with clinical and/or radiologic suspicion for MS between January and December 2024. All patients had a minimum diagnostic evaluation with brain and spinal cord MRI. The 2017 McDonald criteria were applied prospectively, and the 2024 McDonald criteria were applied retrospectively after the initial diagnostic workup and at last follow-up. We investigated (1) the number of patients diagnosed with MS using the 2017 McDonald criteria or the 2024 McDonald criteria, and (2) the diagnostic performance of the 2024 McDonald criteria when applied during the initial diagnostic workup, with an MS diagnosis using the 2017 McDonald criteria as the reference-standard.
50 years).
Citation impact
- FWCI
- 95.20
- Percentile
- 100%
- References
- 40
Authors
12- WBWallace BrownleeCorresponding
Multiple Sclerosis Society, UCL Biomedical Research Centre, National Hospital for Neurology and Neurosurgery, University College London
- DMDavide Maccarrone
Multiple Sclerosis Society, National Hospital for Neurology and Neurosurgery, University College London, Sapienza University of Rome
- RNRiccardo Nistri
Great Ormond Street Hospital, Multiple Sclerosis Society, National Hospital for Neurology and Neurosurgery, University College London
- CYCharmaine Yam
Multiple Sclerosis Society, National Hospital for Neurology and Neurosurgery, University College London
- HWHeather Wilson
Multiple Sclerosis Society, National Hospital for Neurology and Neurosurgery, University College London
Topics & keywords
- Multiple sclerosis
- McDonald criteria
- Sign (mathematics)
- Kappa
- Optic nerve