articleAdvanced ScienceFeb 15, 2026GOLD OA

Lattice Genome Framework for Regionally Tailored Component‐Level Multi‐Objective Design in Additive Manufacturing

Northwestern Polytechnical University · Agency for Science, Technology and Research · +4 more institutions

PubMed
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Abstract

Lattice structures fabricated by additive manufacturing provide unprecedented opportunities for lightweight design, mechanical regulation, and functional integration. However, their efficient development remains constrained by vast design spaces and complex structure-property relationships. Inspired by the Materials Genome Initiative, we propose a Lattice Genome framework, a data-driven approach that integrates high-throughput simulations and performance databases to systematically map lattice properties. Specifically, we develop a component-level, regionally programmable, multi-objective design strategy for coordinated structure-property regulation. The efficacy of the proposed framework is demonstrated…

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