preprintOpen MINDFeb 20, 2026GREEN OA

An Active Topological Latency Bath for Wetware Computing: A MetaTime Open-EFT Upgrade for Organoid–MEA Architectures

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Abstract

Wetware computing platforms (brain organoids interfaced to microelectrode arrays, MEAs) are commonly engineered as volumetric, electrode-dense readout/control systems embedded in a passive liquid environment. This implicitly treats adaptive computation as a three-dimensional throughput problem and relegates the liquid substrate to life support. In the MetaTime Open-EFT bookkeeping, computation is limited by a separation between latency stock ρL (a cached topological scaffold) and execution stock ρI (the online rewrite budget), with mandatory dissipation for irreversible updates bounded below by Landauer. We propose a falsifiable hardware upgrade: an Active Topological Latency Bath (ATLB), in which the…

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Topics & keywords

Keywords
  • Topology (electrical circuits)
  • Computation
  • Latency (audio)
  • Dissipation
  • Network topology
  • Upgrade
  • Bounded function
UN Sustainable Development Goals
  • Responsible consumption and production
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