articleEuropean Urology Open ScienceFeb 20, 2026GOLD OA

Incidental Prostate Cancer Is an Uncommon but Clinically Non-negligible Cause of Death in Selected Long-term Survivors of Urothelial Carcinoma—Oncological Outcomes and a Proposed Follow-up Strategy from a Tertiary Referral Center

University of Bern · The Royal Melbourne Hospital · +4 more institutions

PubMed
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Abstract

Incidental prostate cancer is detected frequently in men undergoing radical cystoprostatectomy for bladder cancer and is usually of low risk. While short-term outcomes are dominated by urothelial carcinoma, advanced prostate cancer features contribute to late mortality. Selective prostate-specific antigen surveillance should be considered in long-term survivors with higher-risk prostate cancer pathology. Incidental prostate cancer is frequently identified in men undergoing radical cystoprostatectomy for urothelial carcinoma of the bladder. While usually clinically insignificant, its long natural history raises questions about long-term impact as systemic therapies prolong bladder cancer survival. The aim of…

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