The Role of Five Key Minerals (Cu, Se, Zn, Co, Fe) in Reproductive Function of Female Cattle: Current Insights and Future Directions

Reproductive efficiency in female cattle is significantly influenced by micronutrient status, particularly the availability and balance of essential trace minerals. Selenium, copper, zinc, cobalt, and iron serve as critical components of enzymatic systems, antioxidant defense networks, hormone synthesis, and cellular metabolism, collectively sustaining reproductive health. This review integrates current research evidence on the physiological functions and molecular mechanisms through which these five trace minerals regulate reproductive performance in female cattle, with a specific focus on iron-an often overlooked element-highlighting the novelty of this synthesis. Both deficiency and excess of these minerals…