Built-In Electric Field-Assisted Enzyme Catalytic Amplification with ZnO/CIS Heterojunctions for Photoelectrochemical Immunoassay
Nankai University · Key Laboratory of Guangdong Province · +2 more institutions
Abstract
This study presents a ZnO/CdIn2S4 (ZnO/CIS) heterojunction-based photoelectrochemical immunosensor for sensitive prostate-specific antigen (PSA) detection. The separation and directional transport of photogenerated charge carriers are enhanced by the built-in electric field at the heterojunction interface, resulting in an increased initial photocurrent. Following immunocomplex formation, alkaline phosphatase-catalyzed ascorbic acid serves as an electron donor to quench photogenerated holes for signal amplification. Density functional theory (DFT) calculations and systematic electrochemical characterizations verify the critical role of the built-in electric field in enhancing charge separation and transfer. The…
Citation impact
- FWCI
- 54.79
- Percentile
- 100%
- References
- 42
Authors
6- HWHaiyang Wang
Nankai University, Key Laboratory of Guangdong Province, Fuzhou University
- MXMingdi XuCorresponding
Fujian University of Technology
- DWDan Wu
Key Laboratory of Guangdong Province, Fuzhou University
- DTDongyang Tie
Key Laboratory of Guangdong Province, Fuzhou University
- MLMeijin LiCorresponding
Key Laboratory of Guangdong Province, Fuzhou University
Topics & keywords
- Heterojunction
- Electric field
- Detection limit
- Linear range
- Ascorbic acid
- Charge carrier
- Immunoassay
- Electrochemistry