articleCritical Care MedicineMar 23, 2026Closed access

Executive Summary: Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026

University of Michigan · VA Ann Arbor Healthcare System · +107 more institutions

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Abstract

The Surviving Sepsis Campaign (SSC): International Guidelines for Management of Sepsis and Septic Shock 2026 provide guidance on the identification and management of sepsis in adult patients with sepsis. They were developed according to Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) methodology. This executive summary reviews the history, methodology, content, and major changes since the 2021 guidelines. HISTORY AND SPONSORSHIP OF THE GUIDELINES The SSC has published guidelines for the management of sepsis and septic shock in 2004, 2008, 2012, 2016, and 2021. The 2026 SSC guidelines are an update from 2021 and focus on evidence published through June 2025. The guidelines are…

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