articleJAMAMar 23, 2026Closed access

Embracing Bayesian Methods in Clinical Trials

JJJ. Jack LeeFEFrank E. HarrellLMLisa M. LaVangeDJDavid J. Spiegelhalter

The University of Texas MD Anderson Cancer Center · Vanderbilt University · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

This Perspective discusses the importance of the US Food and Drug Administration’s draft guidance on the use of bayesian methods in clinical trials because it underscores its commitment to modernizing clinical research.

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4
total citations
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94.96
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99%
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5
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Authors

4

Topics & keywords

Topics
Keywords
  • Clinical trial
  • Bayesian probability
  • Perspective (graphical)
  • Food and drug administration
  • Bayes' theorem
  • Drug trial
  • MEDLINE
  • Drug development
UN Sustainable Development Goals
  • Zero hunger
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