Cell Replication as Inertial Transmission: An Energy-Efficiency Perspective

This paper proposes that cell replication is inertial transmission—the transmission of molecular recognition inertia (DNA base pairing), mechanical inertia (organelle transport via cytoskeleton), and informational structural inertia (epigenetic mark inheritance) across generations. It introduces the investment-maintenance dichotomy and the concept of “inertial rupture” to explain cancer, aging, and developmental abnormalities, providing a unified energy-efficiency framework for cell biology.