IVUS-Guided versus Angiography-Guided PCI in Unprotected Left Main Coronary Disease
Vita-Salute San Raffaele University · IRCCS Policlinico San Donato · +28 more institutions
Abstract
Percutaneous coronary intervention (PCI) is increasingly used for revascularization of unprotected left main coronary artery disease. Whether intravascular ultrasonographic (IVUS) guidance during PCI results in better clinical outcomes than conventional angiographic guidance alone is uncertain.
In an international, multicenter, open-label trial, we randomly assigned patients with unprotected left main coronary artery disease in a 1:1 ratio to undergo either IVUS-guided PCI or angiography-guided PCI. The primary end point was a patient-oriented composite of any stroke, any myocardial infarction, any revascularization, or death from any cause at the longest follow-up.
Citation impact
- FWCI
- 138.60
- Percentile
- 100%
- References
- 28
Authors
24- LTLuca TestaCorresponding
Vita-Salute San Raffaele University, IRCCS Policlinico San Donato
- JMJ M De La Torre Hernandez
Marqués de Valdecilla University Hospital, Instituto de Investigación Marqués de Valdecilla
- GLGiovanni Luigi De Maria
John Radcliffe Hospital, University of Oxford
- DADaniel A. Jones
St Bartholomew's Hospital, Queen Mary University of London, Barts Health NHS Trust, William Harvey Research Institute
- PPPablo Piñón-Esteban
Complexo Hospitalario Universitario A Coruña
Topics & keywords
- Conventional PCI
- Left main coronary artery disease
- Coronary artery disease
- Incidence (geometry)
- Myocardial infarction
- Percutaneous coronary intervention
- Good health and well-being