Anorexia Nervosa as a Stuck Program Mode of the Candida albicans Biochemical Computer

Wested · University of Oklahoma Health Sciences Center

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Abstract

Anorexia nervosa (AN) carries the highest mortality rate of any psychiatric disorder, with relapse rates of 30-50% following weight restoration. The persistence of the condition despite aggressive refeeding remains unexplained. Monteleone et al. (2015) demonstrated that endocannabinoid responses to hedonic eating remain abnormal in weight-restored AN patients, indicating that the physiological disruption outlasts the caloric deficit. This paper applies the biochemical computer framework (Craddock, 2026a; 2026b) to propose that AN represents a stuck program mode in which the organism Candida albicans has locked host feeding behavior into a substrate restriction phase through sustained modulation of…

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Topics & keywords

Keywords
  • Anorexia nervosa
  • Candida albicans
  • Endocannabinoid system
  • Organism
  • Estrogen
  • Mediator
  • Starvation
  • Colonization
UN Sustainable Development Goals
  • Good health and well-being
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