Synthetic Nanoparticles for Vaccines and Immunotherapy

The immune system plays a critical role in our health. No other component of human physiology plays a decisive role in as diverse an array of maladies, from deadly diseases with which we are all familiar to equally terrible esoteric conditions: HIV, malaria, pneumococcal and influenza infections; cancer; atherosclerosis; autoimmune diseases such as lupus, diabetes, and multiple sclerosis. The importance of understanding the function of the immune system and learning how to modulate immunity to protect against or treat disease thus cannot be overstated. Fortunately, we are entering an exciting era where the science of immunology is defining pathways for the rational manipulation of the immune system at the…

• UD
  U.S. Department of Defense

  Award: W911NF-13-D-0001
• HH
  Howard Hughes Medical Institute

  Award: D-0001
• BA
  Bill and Melinda Gates Foundation
• RI
  Ragon Institute of MGH, MIT and Harvard
• NI
  National Institutes of Health

  Awards: CA172164, AI091693, -0001, CA174795
• NC
  National Cancer Institute

  Award: CA174795
• NI
  National Institute of Allergy and Infectious Diseases

  Award: AI111860