Metabolism, Diabetes, and Cancer

This cluster of papers explores the role of AMP-activated protein kinase (AMPK) in regulating cellular metabolism, including its involvement in glucose and lipid metabolism, insulin signaling, mitochondrial homeostasis, and the potential impact on cancer risk. The cluster also delves into the mechanisms of action of metformin, a drug known to activate AMPK and its effects on cellular energy balance and gene expression regulation.