CS

Calcium signaling and nucleotide metabolism

This cluster of papers explores the evolution, function, and dysregulation of lysosomal calcium signaling, focusing on the role of two-pore channels, NAADP, TRPML1, and cyclic ADP-ribose in intracellular calcium release and endolysosomal trafficking. It also investigates the implications of these mechanisms in diseases such as mucolipidosis type IV and lysosomal storage disorders.

14,008
Publications
318,037
Citations

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