Cancer Mechanisms and Therapy

This cluster of papers focuses on the role of Pim oncogenes, particularly Pim-1 and Pim-2 kinases, in promoting tumorigenesis, cancer progression, and metastasis. The cluster also explores the potential of targeting Pim kinases as a therapeutic approach, with a specific emphasis on their involvement in cell survival pathways, phosphorylation of key proteins, and their association with hematological malignancies.