Type 2 diabetes in East Asians: similarities and differences with populations in Europe and the United States

There is an epidemic of diabetes in Asia. Type 2 diabetes develops in East Asian patients at a lower mean body mass index (BMI) compared with those of European descent. At any given BMI, East Asians have a greater amount of body fat and a tendency to visceral adiposity. In Asian patients, diabetes develops at a younger age and is characterized by early β cell dysfunction in the setting of insulin resistance, with many requiring early insulin treatment. The increasing proportion of young-onset and childhood type 2 diabetes is posing a particular threat, with these patients being at increased risk of developing diabetic complications. East Asian patients with type 2 diabetes have a higher risk of developing…

• CU
  Chinese University of Hong Kong
• IA
  Innovation and Technology Fund

  Awards: ITS/088/08, ITS/487/09FP, ITS/130/11
• HK
  Hong Kong Government