The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
HRHeather R. ChristofkMGMatthew G. Vander HeidenMHMarian H. HarrisARArvind RamanathanRERobert E. Gerszten
Center for Systems Biology · Harvard University · +4 more institutions
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Abstract
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2,808
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Authors
9- HRHeather R. ChristofkCorresponding
Center for Systems Biology, Harvard University
- MGMatthew G. Vander Heiden
Center for Systems Biology, Harvard University
- MHMarian H. Harris
Boston Children's Hospital
- ARArvind Ramanathan
Broad Institute
- RERobert E. Gerszten
Harvard University, Massachusetts General Hospital, Broad Institute
Topics & keywords
Topics
Keywords
- Warburg effect
- Pyruvate kinase
- Glycolysis
- PKM2
- Anaerobic glycolysis
- Biology
- Carcinogenesis
- Kinase
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