A Catalog of Reference Genomes from the Human Microbiome

The human microbiome refers to the community of microorganisms, including prokaryotes, viruses, and microbial eukaryotes, that populate the human body. The National Institutes of Health launched an initiative that focuses on describing the diversity of microbial species that are associated with health and disease. The first phase of this initiative includes the sequencing of hundreds of microbial reference genomes, coupled to metagenomic sequencing from multiple body sites. Here we present results from an initial reference genome sequencing of 178 microbial genomes. From 547,968 predicted polypeptides that correspond to the gene complement of these strains, previously unidentified ("novel") polypeptides that…

• CA
  Crohn's and Colitis Foundation
• BI
  Broad Institute
• CA
  Crohn's and Colitis Foundation of Canada
• UG
  Universiteit Gent
• VR
  Vlaamse regering
• NI
  National Institutes of Health

  Awards: HG003079, U54-HG003273